Roshi meets up with him again at the 22nd Tenkaichi Budockai to have his students defeat Roshi's students who did well at the last one. When Tsurusen'in learns that Son Goku was responsible for his brother Tao Pai Pai's supposed death, he orders Tenshinhan to kill Goku in the final round. On one of the nights of the tournament, he attempted to assassinate Goku but failed. At the final round of the tournament, he had Chaozu use telekinesis to freeze Goku so Tenshinhan could kill him. But Tenshinhan rejected the help and wanted to beat him with his own skills, which Chaozu agreed to. Tsurusen'in became mad about this and threatened to kill Chaozu before Roshi blasted the twisted martial arts master out of the arena with a Kamehameha wave so they can fight fairly. After that, Tenshinhan and Chaozu left Tsurusen'in because of his evil ways.
One time, in an anime filler arc, when Goku traveled back in time to train with Mutaito, he saw a young Tsurusen'in and Roshi fight over Fanfan. He kidnapped her and made them defeat him to get her back. By the time of the 23rd Tenkaichi Budokai, Tsurusen'in came back with Tao Pai Pai, who was mechanically modified and was set against Tenshinhan. Tenshinhan defeated Tao and Tsurusen'in carried his unconscious brother out of the arena, swearing he will get revenge. He never appeared in the series again after that point.