The Megalodon is the main villain in the 2012 horror film, Jurassic Shark, which is a parody of Jaws and Jurassic Park. Since the Megalodon was a giant prehistoric shark (in real life), the Megalodon in this film, is shown to be large and aggressive. It will target any human that wanders into its own territory.
In the film, the shark is shown to live in a freshwater lake.