Madame Medusa is the main antagonist of The Rescuers. She is a greedy pawn shop owner who plans to keep the world's largest diamond called the "Devil's Eye". For this, and because she cannot fit in the well where it is kept, she kidnaps an orphan girl named Penny. She is assisted by Mr. Snoops and her pet crocodiles Brutus and Nero.
She was voiced by the late Geraldine Page.